Sodium Deoxycholate Burnside

Sodium Deoxycholate

Appearance: White or off-white powder

Purity: ≥98.0%

CAS No.: 302-95-4

Molecular Formula: C24H39NaO4

Molecular Weight: 414.6 g/mol

Packaging: 1-5kg/25kg(aluminum foil bag/carton/cardboard drum)

Sodium Deoxycholate Introduction

Chemical Structure: 

Sodium deoxycholate is a sodium salt of deoxycholic acid, a secondary bile acid produced by the liver and secreted into the small intestine. Its chemical formula is C24H39NaO4, and it belongs to the class of bile salts.Sodium deoxycholate is deoxycholic acid generated by the action of gut microbiota from bovine bile acid, which is then reacted with sodium hydroxide to obtain a sodium salt. It is deoxycholic acid generated by the action of gut microbiota from bovine and sheep bile acid, which is then reacted with sodium hydroxide to obtain a sodium salt.

Solubility: 

Sodium deoxycholate is highly soluble in water and forms clear solutions. This property makes it useful in various applications where solubility in aqueous solutions is required.

Surfactant Properties: 

Sodium deoxycholate acts as a surfactant, meaning it can lower the surface tension of water and promote the dispersion or emulsification of hydrophobic substances in aqueous solutions. This property makes it useful in formulations for detergents, emulsifiers, and solubilizers.

Medical Applications: 

In medicine, sodium deoxycholate is used in various ******ceutical and medical applications. It is commonly used as an ingredient in ******ceutical formulations, including injectable solutions, ointments, creams, and eye drops. It is also used as a solubilizing agent in formulations for drug delivery and as an excipient in ******ceutical preparations

Detergent and Cleaning Applications: 

Sodium deoxycholate is utilized in detergent formulations, especially in laboratory and industrial settings, due to its ability to solubilize lipids and proteins. It is often used in cleaning solutions for removing fatty residues and proteinaceous contaminants from surfaces and equipment.

Biological Research: 

Sodium deoxycholate is frequently employed in biological research as a reagent for cell lysis and protein extraction. It disrupts cell membranes and solubilizes cellular components, making it useful for isolating proteins and nucleic acids from cells and tissues.

Cosmetic Applications: 

In cosmetics, sodium deoxycholate is sometimes used in formulations for skincare products due to its emulsifying and solubilizing properties. It may be included in creams, lotions, and serums for its potential benefits in enhancing product stability and skin penetration of active ingredients.

Safety Considerations: 

While sodium deoxycholate is generally regarded as safe for its intended uses, it is important to handle it with care due to its detergent properties and potential irritant effects on mucous membranes and skin. Proper safety precautions should be followed when handling and using sodium deoxycholate in laboratory, industrial, and medical settings.

In summary, sodium deoxycholate is a versatile compound with diverse applications in medicine, chemistry, and biology. Its surfactant properties make it useful in ******ceutical formulations, cleaning solutions, biological research, and cosmetic products, among other applications.

Process: Deoxycholic Acid → Sodium Salt Production → Drying → Packing → Storage 

Chenlv Herb Sodium Deoxycholate Application and Dosage Forms

Sodium deoxycholate is widely used in ******ceuticals and it can be used to make vaccine, spray, etc.

● Penetration Enhancer

Sodium deoxycholate is used as the penetration enhancer to prepare the human granulocyte macrophage colony stimulating factor spray, which takes into account the dual functions of stabilizer and absorption enhancer. It not only acts as a stabilizer for anti oxygen enhancement of the main drug, but also plays a role in promoting the transdermal absorption of the main drug, without any damage to the biofilm or skin, can fully improve the local or systemic bioavailability of the main drug body, and can be biodegraded by the body.

Formula: 

● Surfactant   

Sodium deoxycholate is an important anionic surfactant. Using lecithin with good biocompatibility as the outer coating material and sodium deoxycholate as a surfactant for emulsification, perflubron liposome nanospheres with good water solubility and negative surface charge were obtained.       

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