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After 10 weeks, the group that added aripiprazole showed the most improvements

Published date: May 27, 2024
  • Location: United States

After 10 weeks, the group that added aripiprazole showed the most improvements. They had a significant increase in well-being compared with the group that switched to bupropion. The groups with either of the added drugs had less depression symptoms than the group that switched to bupropion. Symptoms improved in 29% of patients with added aripiprazole and 28% of patients with added bupropion. But they improved in only 19% of those who switched to bupropion.


 


“Often, unless a patient responds to the first treatment prescribed for depression, physicians follow a pattern in which they try one treatment after another until they land on an effective medication,” says lead researcher Dr. Eric J. Lenze of the Washington University in St. Louis. “It would be beneficial to have an evidence-based strategy we can rely on to help patients feel better as quickly as possible.”


 


After 10 weeks, the group that added aripiprazole showed the most improvements. They had a significant increase in well-being compared with the group that switched to bupropion. The groups with either of the added drugs had less depression symptoms than the group that switched to bupropion. Symptoms improved in 29% of patients with added aripiprazole and 28% of patients with added bupropion. But they improved in only 19% of those who switched to bupropion.


 


“Often, unless a patient responds to the first treatment prescribed for depression, physicians follow a pattern in which they try one treatment after another until they land on an effective medication,” says lead researcher Dr. Eric J. Lenze of the Washington University in St. Louis. “It would be beneficial to have an evidence-based strategy we can rely on to help patients feel better as quickly as possible.”


 


After 10 weeks, the group that added aripiprazole showed the most improvements. They had a significant increase in well-being compared with the group that switched to bupropion. The groups with either of the added drugs had less depression symptoms than the group that switched to bupropion. Symptoms improved in 29% of patients with added aripiprazole and 28% of patients with added bupropion. But they improved in only 19% of those who switched to bupropion.


 


“Often, unless a patient responds to the first treatment prescribed for depression, physicians follow a pattern in which they try one treatment after another until they land on an effective medication,” says lead researcher Dr. Eric J. Lenze of the Washington University in St. Louis. “It would be beneficial to have an evidence-based strategy we can rely on to help patients feel better as quickly as possible.”


 


After 10 weeks, the group that added aripiprazole showed the most improvements. They had a significant increase in well-being compared with the group that switched to bupropion. The groups with either of the added drugs had less depression symptoms than the group that switched to bupropion. Symptoms improved in 29% of patients with added aripiprazole and 28% of patients with added bupropion. But they improved in only 19% of those who switched to bupropion.


 


“Often, unless a patient responds to the first treatment prescribed for depression, physicians follow a pattern in which they try one treatment after another until they land on an effective medication,” says lead researcher Dr. Eric J. Lenze of the Washington University in St. Louis. “It would be beneficial to have an evidence-based strategy we can rely on to help patients feel better as quickly as possible.”


 


After 10 weeks, the group that added aripiprazole showed the most improvements. They had a significant increase in well-being compared with the group that switched to bupropion. The groups with either of the added drugs had less depression symptoms than the group that switched to bupropion. Symptoms improved in 29% of patients with added aripiprazole and 28% of patients with added bupropion. But they improved in only 19% of those who switched to bupropion.


 


“Often, unless a patient responds to the first treatment prescribed for depression, physicians follow a pattern in which they try one treatment after another until they land on an effective medication,” says lead researcher Dr. Eric J. Lenze of the Washington University in St. Louis. “It would be beneficial to have an evidence-based strategy we can rely on to help patients feel better as quickly as possible.”

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